MF Lefebvre*, NH Claussen*, NP Mitchell, HJ Gustafson, SJ Streichan. Geometric control of Myosin-II orientation during axis elongation. eLife (2023)


NP Mitchell*, MF Lefebvre*, V Jain-Sharma*, NH Claussen, MK Raich, HJ Gustafson, Andreas R Bausch, SJ Streichan. Morphodynamic Atlas for Drosophila Development. bioRxiv (2022)

A Chialastri, E Karzbrun, AH Khankhel, MJ Radeke, SJ Streichan, SS Dey. Integrated single-cell sequencing reveals principles of epigenetic regulation of human gastrulation and germ cell development in a 3D organoid model. bioRxiv (2022)

NP Mitchell, D Cislo, S Shankar, Y Lin, BI Shraiman, SJ Streichan. Visceral organ morphogenesis via calcium-patterned muscle contractions. eLife (2022)

NP Mitchell*, D Cislo*. TubULAR: Tracking deformations of dynamic tissues and interfaces in 3D. bioRxiv (2022)

H Gustafson, N Claussen, S De Renzis, SJ Streichan. Patterned mechanical feedback establishes a global myosin gradient. Nature Communications (2022)


E Karzbrun, AH Khankhel, HC Megale, SMK Glasauer, Y Wyle, G Britton, A Warmflash, KS Kosik, ED Siggia, BI Shraiman, SJ Streichan. Human neural tube morphogenesis in vitro by geometric constraints. Nature (2021)

D Cislo, H Qin, F Yang, MJ Bowick, SJ Streichan. Active Cell Divisions Generate Exotic Fourfold Orientationally Ordered Phase in Living Tissue. bioRxiv (2021)


W Dai, X Guo, Y Cao, JA Mondo, JP Campanale, BJ Montell, H Burrous, SJ Streichan, N Gov, WJ Rappel, DJ Montell. Tissue topography steers migrating Drosophila border cells. Science (2020)

M Serra, S Streichan, M Chuai, CJ Weijer, L Mahadevan. Dynamic morphoskeletons in development. PNAS (2020)

N Noll, SJ Streichan, BI Shraiman. Variational method for image-based inference of internal stress in epithelial tissues. PRX (2020)

G Duclos, R Adkins, D Banerjee, MSE Peterson, M Varghese, I Kolvin, A Baskaran, RA Pelcovits, TR Powers, A Baskaran, F Toschi, MF Hagan, SJ Streichan, V Vitelli, DA Beller, Z Dogic. Topological structure and dynamics of three-dimensional active nematics. Science 367 (6482), 1120-1124 (2020)

DY Chen, J Crest, SJ Streichan, D Bilder. Extracellular matrix stiffness cues junctional remodeling for 3D tissue elongation. Nature Communications 10 (1), 1-15 (2020)


* = these authors contributed equally


Earlier work

Streichan SJ, Lefebvre MF, Noll N, Wieschaus EF, Shraiman BI.  Global morphogenetic flow is accurately predicted by the spatial distribution of myosin motors. eLife 7 (2018)

Noll N, Mani M, Heemskerk I, Streichan SJ, Shraiman BI.  2017.  Active tension network model suggests an exotic mechanical state realized in epithelial tissues. Nature Physics 153:948–7. (2017)

Lignell A, Kerosuo L, Streichan SJ, Cai L, Bronner ME.  Identification of a neural crest stem cell niche by Spatial Genomic Analysis.. Nat Commun. 8(1):1830 (2017)

Chan KG, Streichan SJ, Trinh LA, Liebling M.  Simultaneous Temporal Superresolution and Denoising for Cardiac Fluorescence Microscopy. IEEE Transactions on Computational Imaging. 2:348–358 (2016).

Chen D-Y, Lipari KR, Dehghan Y, Streichan SJ, Bilder D.  Symmetry Breaking in an Edgeless Epithelium by Fat2-Regulated Microtubule Polarity. Cell Rep. 15(6):1125-33 (2016)

Heemskerk I, Streichan SJ.  Tissue cartography: compressing bio-image data by dimensional reduction. Nat Methods. 12(12):1139-42. (2015)

Revenu C, Streichan SJ, Donà E, Lecaudey V, Hufnagel L, Gilmour D.  Quantitative cell polarity imaging defines leader-to-follower transitions during collective migration and the key role of microtubule-dependent adherens junction formation. Development. 141(6):1282-91. (2014)

Streichan SJ, Hoerner CR, Schneidt T, Holzer D, Hufnagel L.  Spatial constraints control cell proliferation in tissues. Proc Natl Acad Sci U S A. 111(15):5586-91 (2014)

Fabrowski P, Necakov AS, Mumbauer S, Loeser E, Reversi A, Streichan S, Briggs JAG, De Renzis S.  Tubular endocytosis drives remodeling of the apical surface during epithelial morphogenesis in Drosophila.. Nat Commun. 4:2244 (2013)

Puliafito A, Hufnagel L, Neveu P, Streichan SJ, Sigal A, D Fygenson K, Shraiman BI.  Collective and single cell behavior in epithelial contact inhibition.. Proc Natl Acad Sci U S A. 109(3):739-44 (2012)

Krzic U, Gunther S, Saunders TE, Streichan SJ, Hufnagel L. Multiview light-sheet microscope for rapid in toto imaging. Nat Methods. 9(7):730-3 (2012)

Streichan SJ, Valentin G, Gilmour D, Hufnagel L.  Collective cell migration guided by dynamically maintained gradients. Phys Biol. 8(4):045004 (2011)